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Chimeric antigen receptor (CAR) T-cell therapy

  • Category
    Science & Technology
  • Published
    10th Feb, 2023


According to a study, long-term response to autologous anti-CD19 chimeric antigen receptor T-cells in relapsed or refractory ‘B cell acute lymphoblastic leukemia’.


  • A type of treatment in which a patient's T cells (a type of immune system cell) is changed in the laboratory so they will attack cancer cells.
  • T cells are taken from a patient’s blood. Then the gene for a special receptor that binds to a certain protein on the patient’s cancer cellsis added to the T cells in the laboratory.
  • The special receptor is called a chimeric antigen receptor (CAR).
  • Large numbers of the CAR T cells are grown in the laboratory and given to the patient by infusion.
  • Chimeric antigen receptor T-cell therapy is used to treat certain blood cancers, and it is being studied in the treatment of other types of cancer.
  • Also called CAR T-cell therapy.

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