Economic loss: Neglected Tropical Diseases can cause chronic ill-health, slow development, inability to work and disfigurement. This may range from the elephantine leg of filariasis to the facial lesions of leishmaniasis.
Poverty: These factors, in turn, reduce the patient’s ability to earn a steady income, intensify ostracism and further poverty.
High mortality rate: Regionally these diseases not only affect a large number of people and carry high mortality and morbidity; they also affect people’s productive and social lives.
Discrimination: Leprosy, lymphatic filariasis and yaws can cause disabilities and visible deformities that can lead those affected to be stigmatized, discriminated against and marginalized and thus kept from participating in the normal family or community life or from earning their livelihoods in settings that are already poor in resources.
Social isolation: Effects from NTDs such as deformed legs and blindness results in social isolation. Social isolation and physical ailments make working difficult for people with NTDs.
Women & Children: Women and children are at particularly high risk for these diseases, which have a negative impact on reproductive and general health and on nutritional status as well. Amongst children, infection leads to malnutrition, cognitive impairment, stunted growth, and the inability to attend school.