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5th June 2025 (11 Topics)

MASLD Disease

Context

Naruvi Hospitals, Vellore, in collaboration with The Hindu, is organizing a webinar on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). The session aims to raise awareness about this silent yet rising liver disorder linked to lifestyle-related metabolic conditions like obesity, insulin resistance, and Type 2 diabetes. The webinar will be held on Sunday at 11:30 a.m., featuring leading hepatology experts.

What is MASLD?

  • MASLD (Metabolic dysfunction–associated steatotic liver disease), previously termed Non-Alcoholic Fatty Liver Disease (NAFLD), is a chronic liver condition caused by fat accumulation in the liver not due to alcohol consumption.
  • It is now classified under the broader umbrella of metabolic disorders.
  • It is often asymptomatic in early stages, hence termed a “silent liver disease”.

Causes and Risk Factors

  • MASLD is strongly associated with metabolic syndrome, including:
    • Obesity
    • Type 2 Diabetes Mellitus
    • Hyperlipidemia (High blood lipids)
    • Hypertension
    • Insulin resistance
Public Health Relevance
  • India has a rising incidence of lifestyle diseases, making MASLD a major non-communicable disease (NCD) of concern.
  • Estimated to affect over 25% of the global adult population, with increased prevalence in urban India due to sedentary lifestyles and unhealthy diets.
  • Early detection and lifestyle modifications (diet, exercise, weight loss) are critical for prevention and management.
Medical and Policy Implications
  • MASLD, if undetected, can progress to liver fibrosis, cirrhosis, or even hepatocellular carcinoma.
  • National health policies increasingly emphasize preventive care and NCD screening, which could integrate MASLD diagnostics.
  • The Indian Council of Medical Research (ICMR) and Ministry of Health may consider MASLD within broader NCD control frameworks in future.

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