28 September is observed as the World Rabies Day. This year’s "Breaking Rabies Boundaries" highlights that One Health is not for a selected few but for everyone.
About Rabies
Rabies is a vaccine-preventable, zoonotic, viral disease affecting the central nervous system.
Transmission: In up to 99% of the human rabies cases, dogs are responsible for virus transmission.
It is an RNA virus of the rhabdovirus family that can affect the body in one of two ways.
It can enter the peripheral nervous system directly and migrate to the brain.
It can also replicate within muscle tissue. From here, it enters the nervous system through the neuromuscular junctions.
Once inside the nervous system, the virus produces acute inflammationof the brain
Types:
Furious or encephalitic rabies: A person with it is more likely to experience hyperactivity and hydrophobia.
Paralytic or “dumb” rabies: It causes paralysis as a dominant symptom.
Vaccines: Newer rabies immunoglobulin (Rabies Ig) and the rabies vaccine are essential for post-exposure prophylaxis (PEP) against rabies.
Rabies Ig is specifically used for category 3 bites, which involve severe exposure such as transdermal bites or scratches, and provides immediate protection by supplying ready-made antibodies.
Situation in India: Rabies in India, as of 2021, caused 59,000 deaths, representing 33% of the global total.
Notably, 96% of these fatalities resulted from dog bites.
The overall economic cost of dog-mediated Rabies was estimated to be $8.6 billion.