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27th September 2024 (10 Topics)

World Rabies Day

Context

28 September is observed as the World Rabies Day. This year’s "Breaking Rabies Boundaries" highlights that One Health is not for a selected few but for everyone.

About Rabies

  • Rabies is a vaccine-preventable, zoonotic, viral disease affecting the central nervous system.
  • Transmission: In up to 99% of the human rabies cases, dogs are responsible for virus transmission. 
  • It is an RNA virus of the rhabdovirus family that can affect the body in one of two ways.
    • It can enter the peripheral nervous system directly and migrate to the brain.
    • It can also replicate within muscle tissue. From here, it enters the nervous system through the neuromuscular junctions.
  • Once inside the nervous system, the virus produces acute inflammationof the brain
  • Types:
    • Furious or encephalitic rabies: A person with it is more likely to experience hyperactivity and hydrophobia.
    • Paralytic or “dumb” rabies: It causes paralysis as a dominant symptom.
  • Vaccines: Newer rabies immunoglobulin (Rabies Ig) and the rabies vaccine are essential for post-exposure prophylaxis (PEP) against rabies.
    • Rabies Ig is specifically used for category 3 bites, which involve severe exposure such as transdermal bites or scratches, and provides immediate protection by supplying ready-made antibodies.
  • Situation in India: Rabies in India, as of 2021, caused 59,000 deaths, representing 33% of the global total.
    • Notably, 96% of these fatalities resulted from dog bites.
    • The overall economic cost of dog-mediated Rabies was estimated to be $8.6 billion.
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