Recently scientists from the US have developed the first bio-electronic medicine -- an implantable, biodegradable wireless device that speeds nerve regeneration and improves the healing of a damaged nerve.
The technology called as "bio-electronic medicine" provides therapy and treatment over a clinically relevant period of time and directly at the site where it's needed, thereby reducing side effects or risks associated with conventional, permanent implants.
While the device has not been tested in humans, the findings offer promise as a future therapeutic option for nerve injury patients.
Context
Recently scientists from the US have developed the first bio-electronic medicine -- an implantable, biodegradable wireless device that speeds nerve regeneration and improves the healing of a damaged nerve.
The technology called as "bio-electronic medicine" provides therapy and treatment over a clinically relevant period of time and directly at the site where it's needed, thereby reducing side effects or risks associated with conventional, permanent implants.
While the device has not been tested in humans, the findings offer promise as a future therapeutic option for nerve injury patients.
About
Researchers at the Washington University in the US have developed a device that delivers regular pulses of electricity to damaged peripheral nerves in rats after a surgical repair process, accelerating the regrowth of nerves in their legs and enhancing the ultimate recovery of muscle strength and control
The device is of the size of a dime and the thickness of a sheet of paper and operates for about two weeks before naturally absorbing into the body.
The device is powered and controlled wirelessly by a transmitter outside the body that acts much like a cell-phone charging mat.
For cases requiring surgery, standard practice is to administer some electrical stimulation during the surgery to aid recovery. However, until now, doctors have lacked a means to continuously provide that added boost at various time points throughout the recovery and healing process.
New versions can provide electrical pulses for weeks before degrading. T
It can degrade in the body, thereby eliminating need of a second surgery to remove a non-biodegradable device. This reduces additional risk to the patient.
Significance
The researchers envision that such transient engineered technologies one day could complement or replace pharmaceutical treatments for a variety of medical conditions in humans.
These engineered systems provide active, therapeutic function in programmable, dosed format and then naturally disappear into body, without trace.
With this device, it has been shown that electrical stimulation given on scheduled basis during surgery can further enhance nerve recovery.
No adverse biological effects from device and its reabsorption were found.