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6th December 2024 (11 Topics)

Marburg Virus Disease (Bleeding Eye Virus)

Context

The Marburg virus disease (MVD) outbreak in Rwanda has seen progress, and the World Health Organization (WHO) updated, that the 42-day countdown to declare the outbreak over will begin if there are no new cases.

What is Marburg Virus Disease (MVD)?

  • The Marburg virus is a deadly virus that causes Marburg virus disease (MVD), also known as the ‘bleeding eye virus’ because one of its symptoms is bleeding from the eyes.
  • The virus can also cause organ failure and death.
  • The virus is mainly transmitted from fruit bats, and human-to-human transmission happens through contact with the bodily fluids of an infected person, such as blood, vomit, or saliva.
  • The virus is highly contagious and can spread directly through bodily fluids or indirectly by touching contaminated surfaces.
  • Symptoms of Marburg Virus Disease
  • High fever
  • Fatigue and body aches
  • Watery diarrhea and abdominal cramps (starting around the third day)
  • Non-itchy rashes (usually between the second and seventh day)
  • As the disease progresses, bleeding starts, usually from the eyes, but can also occur from the nose, gums, and vagina. This bleeding is what gives the virus its common name.
  • Other symptoms include confusion and disorientation, which can happen due to the virus affecting the brain. As the disease worsens, it can lead to multi-organ failure, which can be fatal.
  • The virus is highly contagious.
  • Diagnosis: The Marburg virus can be diagnosed using two main tests:
    • ELISA (Enzyme-Linked Immunosorbent Assay)
    • RT-PCR (Reverse Transcription Polymerase Chain Reaction)
  • Treatment: There is no specific antiviral treatment for MVD. Instead, supportive care is provided to help manage symptoms, which includes rehydration, pain relief, and treatment for shock or other complications.
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