What's New :
Open Webinar for Mains 2021 : Register Now

miR-155

  • Category
    Miscellaneous
  • Published
    25th Jun, 2020

Researchers at the Indian Institute of Technology Madras have identified a specific microRNA (miRNAs) called ‘miR-155’ that is over-expressed in tongue cancer. 

  • Researchers at the Indian Institute of Technology Madras have identified a specific microRNA (miRNAs) called ‘miR-155’ that is over-expressed in tongue cancer. 

What is MiR-155?

  • MiR-155 is a microRNA that in humans is encoded by the MIR155 host gene or MIR155HG. 
  • MiR-155 plays a role in various physiological and pathological processes.
  • Exogenous molecular control in vivo of miR-155 expression may inhibit malignant growth, viral infections, and enhance the progression of cardiovascular diseases.

About MicroRNAs

  • MicroRNAs (miRNAs) are short non?coding RNAs containing 20–24 nucleotides that participate in virtually all biological pathways in animals.
  • They have been found to play important roles in many cancers, in carcinogenesis (start of cancer), malignant transformation and metastasis — the development of secondary cancer.
  • The miRNAs associated with cancer are called ‘Oncomirs’.”
  • Many of the Oncomirs affect cancer by suppressing the performance of tumour-suppressing agents.
  • Some of them can prevent the growth and spread of cancer cells and yet others prevent tumour growth itself.
Enquire Now