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31st May 2024 (14 Topics)

Paediatric inflammatory bowel disease

Context

Inflammatory Bowel Disease (IBD) is making headlines due to increasing awareness and diagnosis among children in India.

What is IBD?

  • IBD is a chronic condition where the body's immune system mistakenly attacks the cells of the digestive tract, causing inflammation and ulcers.
  • Symptoms: This chronic autoimmune condition affects the digestive tract, causing symptoms like fever, abdominal pain, diarrhea (sometimes bloody), and weight loss.
  • Types: There are two main types of IBD:
    • Ulcerative Colitis: Affects only the large intestine (colon).
    • Crohn's Disease: Can affect any part of the digestive tract, from the mouth to the anus.
  • Causes of IBD: The exact cause is still unknown, but several factors contribute to its development:
    • Immune System Dysregulation: Children with IBD often have a weak or overactive immune system that responds inappropriately to environmental triggers like viruses or bacteria.
    • Genetics: There may be a genetic predisposition, as IBD sometimes runs in families.
    • Gut Microbiota: The millions of microorganisms in the human gut play a crucial role. Changes in the gut microbiota, influenced by frequent antibiotic use or westernized diets, are linked to IBD.
    • Environmental Factors: Lifestyle changes and dietary habits can also trigger or exacerbate IBD.

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