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2nd July 2024 (9 Topics)

World’s first Brain Implant to control Epileptic Seizures

Context

Oran Knowlson, a teenager from the UK, recently made headlines for becoming the first person worldwide to receive a brain implant aimed at reducing epileptic seizures. This deep brain stimulation (DBS) device, surgically implanted into his skull and connected to electrodes targeting the brain's thalamus, has successfully reduced his daytime seizures by an impressive 80%.

About DBS device

  • The DBS device delivers constant electrical impulses to disrupt seizure-causing brain signals.
  • It offers a promising alternative for patients resistant to traditional anti-seizure medications or those for whom surgery is not viable.
  • It is surgically placed in the skull, electrodes inserted into the thalamus (brain's relay station).
  • Effectiveness: Reduced Knowlson’s seizures by 80%.
  • Comparison with Existing Treatments:
    • Medication: Many patients are resistant (30%) to available anti-seizure drugs.
    • Surgery: Effective but invasive; removes seizure-originating brain areas.
    • Ketogenic Diet: High-fat, low-carb diet also used to control seizures.

Fact Box:

  • Epilepsy is a condition characterized by recurring seizures due to abnormal brain activity.
  • Causes include head trauma, brain tumors, infections, or genetics.
  • It affects daily life and increases the risk of accidents.
  • Epilepsy Prevalence in India: 3 to 11.9 per 1,000 people (Lancet, 2022).
  • Effectiveness Comparison:
    • DBS: Reduces seizures by about 40%.
    • Surgery: Decreases seizures by nearly 90%.

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