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20th May 2024 (13 Topics)

WHO's updated Bacterial Pathogens Priority List

Context

The World Health Organization (WHO) latest Bacterial Pathogens Priority List (BPPL) highlights 15 families of antibiotic-resistant bacteria, categorized into critical, high, and medium priorities for intervention.

Key Findings:

  • The critical priority pathogens pose significant global threats due to their resistance to treatment and ability to spread resistance to other bacteria.
  • The list covers 24 pathogens, spanning 15 families of antibiotic-resistant bacterial pathogens.

Critical priority:

High priority:

Medium priority: 

  • Acinetobacter baumannii, carbapenem-resistant;
  • Enterobacterales, third-generation cephalosporin-resistant; and
  • Enterobacterales, carbapenem-resistant;
  • Mycobacterium tuberculosis, rifampicin-resistant (included after an independent analysis with parallel tailored criteria, and subsequent application of an adapted multi-criteria decision analysis matrix).
  • Salmonella Typhi, fluoroquinolone-resistant
  • Shigella spp., fluoroquinolone-resistant
  • Enterococcus faecium, vancomycin-resistant
  • Pseudomonas aeruginosa, carbapenem-resistant
  • Non-typhoidal Salmonella, fluoroquinolone-resistant
  • Neisseria gonorrhoeae, third-generation cephalosporin- and/or fluoroquinolone-resistant
  • Staphylococcus aureus, methicillin-resistant
  • Group A streptococci, macrolide-resistant
  • Streptococcus pneumoniae, macrolide-resistant
  • Haemophilus influenzae, ampicillin-resistant
  • Group B streptococci, penicillin-resistant
  • The inclusion of these pathogens in the list underscores their global impact in terms of burden, as well as issues related to transmissibility, treatability, and prevention options.
  • It also reflects the R&D pipeline of new treatments and emerging resistance trends.

PYQ:

Q: Which of the following are the reasons for the occurrence of multi-drug resistance in microbial pathogens in India? 2019.  

  1. Genetic predisposition of some people
  2. Taking incorrect doses of antibiotics to cure diseases
  3. Using antibiotics in livestock farming
  4. Multiple chronic diseases in some people

Select the correct answer using the code given below

  1. 1 and 2
  2. 2 and 3 only
  3. 1, 3 and 4
  4. 2, 3 and 4

Solution: (b)

X

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