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First Woman Reported cured of HIV After Stem Cell Transplant

  • Published
    17th Feb, 2022
Context

A U.S. patient with leukemia has become the first woman and the third person to date to be cured of HIV after receiving a stem cell transplant.

A woman of mixed race was cured of HIV, using a new transplant method involving umbilical cord blood.

About

About HIV:

  • Human Immunodeficiency Virus (HIV) is a lentivirus, which is a sub-classification of the retrovirus.
  • It causes the HIV infection which over time leads to AIDS (Acquired Immunodeficiency Syndrome). 

  • AIDS is a deadly condition in which the affected person’s immune system fails, leading to the spread of life-threatening infections and cancers in his body.
  • HIV demolishes a particular type of WBC(White Blood Cells) and the T-helper cells. This virus also makes copies of itself inside these cells.
  • T-helper cells are also known as CD4 cells.
  • The average survival period for a person affected with HIV without treatment is nine to eleven years, subject to the subtype of HIV.
  • HIV infection can occur by the transference of blood, breast milk, vaginal fluid, semen, or pre-ejaculate.
  • HIV occurs as both free virus particles and as a virus inside the infected immune cells within the above-mentioned bodily fluids.
  • A weak immune system makes a person prone to opportunistic infections and cancer.
  • It becomes difficult for a person infected with this virus to recover from even a minor injury or sickness.

About Stem Cell:

  • A stem cell is a cell with the unique ability to develop into specialized cell types in the body.
  • These cells provide new cells for the body as it grows, and replace specialized cells that are damaged or lost.
  • In the future, they will be used to replace cells and tissues that have been damaged or lost due to disease.
  • Our body is made up of numerous types of cells.
  • Most cells are specialized for particular functions, like the red blood cells that carry oxygen in our bodies through the blood, but they are unable to divide.
  • All stem cells regardless of their source have three general properties:
  • They are capable of dividing and renewing themselves for long periods
  • They are unspecialized
  • They can give rise to specialized cell types

Stem cell therapy:

  • Stem cell therapy, also known as regenerative medicine, promotes the repair response of diseased, dysfunctional, or injured tissue using stem cells or their derivatives.
  • Stem cells may be one of the ways of generating new cells that can be transplanted into the body to replace the damaged or lost cells.
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